BioDiscussion

Effect of rosuvastatin on progression of CIMT in low-risk individuals with subclinical atherosclerosis: The METEOR Trial

Objectives:
After completing this audio conference the participant should be better able to: 1) discuss the study design and rationale for the METEOR trial, 2) understand the place for CIMT measurements in risk prediction, 3) understand the argument for low-risk patient treatment, and 4) apply learnings to provide enhanced patient care.

Title:
Effect of rosuvastatin on progression of carotid intima-media thickness in low-risk individuals with subclinical atherosclerosis: the METEOR Trial.

Authors:
JR Crouse, JS Raichlen, WA Riley, GW Evans, MK Palmer, DH O'Leary, DE Grobbee, ML Bots

Citation:
JAMA 2007 3;297(12):1344-53

Presentation

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Background

BioCritique references

Effect of rosuvastatin on progression of carotid intima-media thickness in low-risk individuals with subclinical atherosclerosis: the METEOR Trial. JR Crouse et al. JAMA 2007 3;297(12):1344-53

Implications of cardiac risk and low-density lipoprotein cholesterol distributions in the United States for the diagnosis and treatment of dyslipidemia: data from National Health and Nutrition Examination Survey 1999 to 2002. JG Keevil et al. Circulation 2007 3;115(11):1363-70

PubMed abstracts

ARBITER: Arterial Biology for the Investigation of the Treatment Effects of Reducing Cholesterol: a randomized trial comparing the effects of atorvastatin and pravastatin on carotid intima medial thickness. AJ Taylor et al. Circulation 2002 10;106(16):2055-60

Arterial Biology for the Investigation of the Treatment Effects of Reducing Cholesterol (ARBITER) 2: a double-blind, placebo-controlled study of extended-release niacin on atherosclerosis progression in secondary prevention patients treated with statins. AJ Taylor et al. Circulation 2004 12;110(23):3512-7

Panelists

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CME Credit Info: 1 Category 1 Credit
Release Date: June 24, 2007
Expiration Date: June 20, 2008

Bulletin Board

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The manner in which the IMT analyses were done should have been adapted to reflect the new insights in the process of of IMT progression and Lesion assessment. A missed opportunity - dutch on Jul 03 5:56 PM

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