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Arthritis & Rheumatology

• Safety and efficacy of the selective costimulation modulator abatacept in patients with rheumatoid arthritis receiving background methotrexate: a 5-year extended phase IIB study. R Westhovens et al. J Rheumatol 2009 4;36(4):736-42
  Panelists: Joel Kremer, MD; Arthur Weaver, M.D., M.S., F.A.C.P., M.A.C.R.
• Rituximab inhibits structural joint damage in rheumatoid arthritis patients with an inadequate response to tumour necrosis factor inhibitor therapies. EC Keystone et al. Ann Rheum Dis 2008 4;():
  Panelists: Paul Emery, MD; Arthur Weaver, M.D., M.S., F.A.C.P., M.A.C.R.

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Cancer

• Adjuvant chemotherapy in older women with early-stage breast cancer. HB Muss et al. N Engl J Med 2009 5;360(20):2055-65
  Panelists: Hyman Muss, MD; Lawrence Shulman, MD

Cardiovascular Disease

• Rosuvastatin to Prevent Vascular Events in Men and Women with Elevated C-Reactive Protein. PM Ridker et al. N Engl J Med 2008 11;():
  Panelists: Robert Chilton, D.O.; Paul Ridker, MD, MPH, FAHA, FACC
• Comparison of pioglitazone vs glimepiride on progression of coronary atherosclerosis in patients with type 2 diabetes: the PERISCOPE randomized controlled trial. SE Nissen et al. JAMA 2008 4;299(13):1561-73
  Panelists: Robert Chilton, D.O.; Vivian Fonseca, M.D.; Steven Nissen, MD, FACC

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Dermatology

• Innovative uses of imiquimod. RB Vender et al. J Drugs Dermatol 2005 1;4(1):58-63
  Panelists: Roy Grekin, MD; Philip LeBoit, MD; Ronald Vender, MD, FRCPC

Diabetes

• Effect of saxagliptin monotherapy in treatment-naïve patients with type 2 diabetes. J Rosenstock et al. Curr Med Res Opin 2009 10;25(10):2401-11
  Panelists: Vivian Fonseca, M.D.; Julio Rosenstock, MD
• Colesevelam HCl Improves Glycemic Control and Reduces LDL-Cholesterol in Patients with Type 2 Diabetes Inadequately Controlled on Sulfonylurea-Based Therapy. VA Fonseca et al. Diabetes Care 2008 5;():
  Panelists: Vivian Fonseca, M.D.; Ronald Goldberg, MD

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Growth-Related Disorders

• Insulin growth factor-based dosing of growth hormone therapy in children: a randomized, controlled study. P Cohen et al. J Clin Endocrinol Metab 2007 7;92(7):2480-6
  Panelists: David Allen, M.D.; Steven Chernausek, MD; Pinchas Cohen, M.D.
• Early recombinant human growth hormone treatment in glucocorticoid-treated children with juvenile idiopathic arthritis: a 3-year randomized study. D Simon et al. J Clin Endocrinol Metab 2007 7;92(7):2567-73
  Panelists: David Allen, M.D.; Paul Czernichow, MD; Stephen LaFranchi, M.D.

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Nephrology

• Predictive cardiovascular risk factors in patients with chronic kidney disease (CKD). M Goicoechea et al. Kidney Int Suppl 2005 1;(93):S35-8
  Panelists: George Bakris, MD; Peter McCullough, M.D., M.P.H.; Donal Reddan, MD
• Rosuvastatin-induced arrest in progression of renal disease. DG Vidt et al. Cardiology 2004 1;102(1):52-60
  Panelists: George Bakris, MD; Peter McCullough, M.D., M.P.H.; Donal Reddan, MD

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Obesity

• Clinical management of metabolic syndrome: report of the American Heart Association/National Heart, Lung, and Blood Institute/American Diabetes Association conference on scientific issues related to management. SM Grundy et al. Circulation 2004;109:551-556.
  Panelists: Roger Blumenthal, M.D.; Scott Grundy, M.D., Ph.D.; Peter Toth, M.D., Ph.D.
• The escalating pandemics of obesity and sedentary lifestyle. A call to action for clinicians. JE Manson et al. Arch Intern Med 2004 2;164(3):249-58
  Panelists: Graciela Alarcon, M.D., M.P.H; Vera Bittner, M.D., M.S.P.H.; JoAnn Manson, M.D., Dr.P.H., M.P.H.

Primary Care

• Prevention of cardiovascular events with an antihypertensive regimen of amlodipine adding perindopril as required versus atenolol adding bendroflumethiazide as required, in the Anglo-Scandinavian Cardiac Outcomes Trial-Blood Pressure Lowering Arm (ASCOT-BPLA): a multicentre randomised controlled trial. B Dahlöf et al. Lancet 2005 9;366(9489):895-906
  Panelists: Robert Chilton, D.O.; Jerome Cohen, M.D.; Peter Sever, PhD, FRCP
• Treatment of rheumatoid arthritis with the selective costimulation modulator abatacept: twelve-month results of a phase iib, double-blind, randomized, placebo-controlled trial. JM Kremer et al. Arthritis Rheum 2005 8;52(8):2263-71
  Panelists: Graciela Alarcon, M.D., M.P.H; John Cush, M.D.; Joel Kremer, MD

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